(E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate
TL;DR: (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate (CAS 1164498-69-4) is a chemical compound with molecular formula C26H29FN4O3 and molecular weight 464.22238 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
ethyl 5-fluoro-3-[[2-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]acetyl]amino]-1H-indole-2-carboxylate
Also Known As: (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate, ethyl 5-fluoro-3-[({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}acetyl)amino]-1H-indole-2-carboxylate, ethyl 5-fluoro-3-[[2-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]acetyl]amino]-1H-indole-2-carboxylate
Technical Specifications
| Molecular Formula | C26H29FN4O3 |
| Molecular Weight | 464.22238 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 77.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 464.22238 Da |
| Heavy Atoms | 34 |
| Complexity | 706.0 |
| SMILES | CCOC(=O)C1=C(C2=C(N1)C=CC(=C2)F)NC(=O)CN3CCN(CC3)C/C=C/C4=CC=CC=C4 |
| InChIKey | AUIDSNCYVYSACM-RMKNXTFCSA-N |
Chemical Property Profile of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate
Property Insights of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate
The XLogP value of 4.4 indicates that (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.7 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate. Following Lipinski's Rule of Five, (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate?
The CAS number of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate is 1164498-69-4.
What is the molecular formula of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate?
The molecular formula of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate is C26H29FN4O3.
What is the molecular weight of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate?
The molecular weight of (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate is 464.22238 g/mol.
Where can I buy (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate?
You can request a quote for (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate?
Yes, CoreyChem provides custom synthesis services for (E)-ethyl 3-(2-(4-cinnamylpiperazin-1-yl)acetamido)-5-fluoro-1H-indole-2-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.