![(E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one structure](/static/products/1164/1164504-99-7.webp)
(E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one
TL;DR: (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one (CAS 1164504-99-7) is a chemical compound with molecular formula C18H20N2O2S and molecular weight 328.12454 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one
Also Known As: 1-(2-methoxyphenyl)-4-[3-(2-thienyl)acryloyl]piperazine, (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one, (2E)-1-[4-(2-methoxyphenyl)piperazinyl]-3-(2-thienyl)prop-2-en-1-one, (E)-1-[4-(2-methoxyphenyl)piperazino]-3-(2-thienyl)prop-2-en-1-one, (2E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-(thiophen-2-yl)prop-2-en-1-one
Technical Specifications
| Molecular Formula | C18H20N2O2S |
| Molecular Weight | 328.12454 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 61.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 328.12454 Da |
| Heavy Atoms | 23 |
| Complexity | 421.0 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)C(=O)/C=C/C3=CC=CS3 |
| InChIKey | QXVUREFSAZDTGS-CMDGGOBGSA-N |
Chemical Property Profile of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one
Property Insights of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one
The XLogP value of 3.1 indicates that (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one. Following Lipinski's Rule of Five, (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one?
The CAS number of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one is 1164504-99-7.
What is the molecular formula of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one?
The molecular formula of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one is C18H20N2O2S.
What is the molecular weight of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one?
The molecular weight of (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one is 328.12454 g/mol.
Where can I buy (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one?
You can request a quote for (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one?
Yes, CoreyChem provides custom synthesis services for (E)-1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-thiophen-2-ylprop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.