![1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine structure](/static/products/1164/1164505-95-6.webp)
1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine
TL;DR: 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine (CAS 1164505-95-6) is a chemical compound with molecular formula C18H18FN3O and molecular weight 311.1434 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E)-3-(4-fluorophenyl)-1-(4-pyridin-2-ylpiperazin-1-yl)prop-2-en-1-one
Also Known As: 1-[3-(4-fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine, (2E)-3-(4-fluorophenyl)-1-(4-(2-pyridyl)piperazinyl)prop-2-en-1-one, (E)-3-(4-fluorophenyl)-1-(4-pyridin-2-ylpiperazin-1-yl)prop-2-en-1-one, 3-(4-fluorophenyl)-1-(4-pyridin-2-ylpiperazin-1-yl)prop-2-en-1-one, (2E)-3-(4-fluorophenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]prop-2-en-1-one
Technical Specifications
| Molecular Formula | C18H18FN3O |
| Molecular Weight | 311.1434 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 36.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 311.1434 Da |
| Heavy Atoms | 23 |
| Complexity | 412.0 |
| SMILES | C1CN(CCN1C2=CC=CC=N2)C(=O)/C=C/C3=CC=C(C=C3)F |
| InChIKey | JYIYODBZPFADMC-RMKNXTFCSA-N |
Chemical Property Profile of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine
Property Insights of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine. With a topological polar surface area (TPSA) of 36.4 Ų, 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine?
The CAS number of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine is 1164505-95-6.
What is the molecular formula of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine?
The molecular formula of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine is C18H18FN3O.
What is the molecular weight of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine?
The molecular weight of 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine is 311.1434 g/mol.
Where can I buy 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine?
You can request a quote for 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine?
Yes, CoreyChem provides custom synthesis services for 1-[3-(4-Fluorophenyl)acryloyl]-4-(2-pyridinyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.