2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one
TL;DR: 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one (CAS 1164507-15-6) is a chemical compound with molecular formula C12H12N2O2S2 and molecular weight 280.03403 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5E)-2-morpholin-4-yl-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one
Also Known As: BIM-0020133.P001, 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one, (E)-2-morpholino-5-(thiophen-2-ylmethylene)thiazol-4(5H)-one, (5E)-2-morpholin-4-yl-5-(thiophen-2-ylmethylidene)-1,3-thiazol-4-one, (5E)-2-(MORPHOLIN-4-YL)-5-[(THIOPHEN-2-YL)METHYLIDENE]-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
Technical Specifications
| Molecular Formula | C12H12N2O2S2 |
| Molecular Weight | 280.03403 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 95.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 280.03403 Da |
| Heavy Atoms | 18 |
| Complexity | 403.0 |
| SMILES | C1COCCN1C2=NC(=O)/C(=C\C3=CC=CS3)/S2 |
| InChIKey | KIXBNLUJUHXGFK-CSKARUKUSA-N |
Chemical Property Profile of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one
Property Insights of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one. The TPSA of 95.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one. Following Lipinski's Rule of Five, 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one?
The CAS number of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one is 1164507-15-6.
What is the molecular formula of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one?
The molecular formula of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one is C12H12N2O2S2.
What is the molecular weight of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one?
The molecular weight of 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one is 280.03403 g/mol.
Where can I buy 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one?
You can request a quote for 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one?
Yes, CoreyChem provides custom synthesis services for 2-(4-morpholinyl)-5-(2-thienylmethylene)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.