![1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine structure](/static/products/1165/116557-96-1.webp)
1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
TL;DR: 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine (CAS 116557-96-1) is a chemical compound with molecular formula C17H18N2OS and molecular weight 298.11398 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E)-1-(4-phenylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Also Known As: 1-phenyl-4-[3-(2-thienyl)acryloyl]piperazine, BIM-0038179.P001, (2E)-1-(4-phenylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one, (E)-1-(4-phenylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one, (E)-1-(4-phenylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
Technical Specifications
| Molecular Formula | C17H18N2OS |
| Molecular Weight | 298.11398 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 51.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 298.11398 Da |
| Heavy Atoms | 21 |
| Complexity | 371.0 |
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=O)/C=C/C3=CC=CS3 |
| InChIKey | DXDYJYNATMSOPE-CMDGGOBGSA-N |
Chemical Property Profile of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
Property Insights of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
The XLogP value of 3.1 indicates that 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The CAS number of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is 116557-96-1.
What is the molecular formula of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The molecular formula of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is C17H18N2OS.
What is the molecular weight of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The molecular weight of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is 298.11398 g/mol.
Where can I buy 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
You can request a quote for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
Yes, CoreyChem provides custom synthesis services for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.