Flurazepam Hydrochloride
TL;DR: Flurazepam Hydrochloride (CAS 1172-18-5) is a chemical compound with molecular formula C21H25Cl3FN3O and molecular weight 459.10474 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one;dihydrochloride
Also Known As: Flurazepam hydrochloride, Flurazepam dihydrochloride, Dalmane, Benozil, Lunipax
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H25Cl3FN3O |
| Molecular Weight | 459.10474 g/mol |
| XLogP | 4.85 |
| Topological Polar Surface Area (TPSA) | 35.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 459.10474 Da |
| Heavy Atoms | 29 |
| Complexity | 540.0 |
| Melting Point | 406 to 424 °F (decomposes) (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) |
| SMILES | CCN(CC)CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F.Cl.Cl |
| InChIKey | ZIIJJOPLRSCQNX-UHFFFAOYSA-N |
Chemical Property Profile of Flurazepam Hydrochloride
Property Insights of Flurazepam Hydrochloride
The XLogP value of 4.85 indicates that Flurazepam Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.9 Ų, Flurazepam Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Flurazepam Hydrochloride has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Flurazepam Hydrochloride?
The CAS number of Flurazepam Hydrochloride is 1172-18-5.
What is the molecular formula of Flurazepam Hydrochloride?
The molecular formula of Flurazepam Hydrochloride is C21H25Cl3FN3O.
What is the molecular weight of Flurazepam Hydrochloride?
The molecular weight of Flurazepam Hydrochloride is 459.10474 g/mol.
Where can I buy Flurazepam Hydrochloride?
You can request a quote for Flurazepam Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Flurazepam Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Flurazepam Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.