Combretastatin D1
TL;DR: Combretastatin D1 (CAS 117709-78-1) is a chemical compound with molecular formula C18H16O5 and molecular weight 312.09976 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
13-hydroxy-3,6,15-trioxatetracyclo[14.2.2.110,14.02,4]henicosa-1(19),10(21),11,13,16(20),17-hexaen-7-one
Also Known As: Combretastatin D1, (3R,4S)-(-)-combretastatin D-1, 13-hydroxy-3,6,15-trioxatetracyclo[14.2.2.110,14.02,4]henicosa-1(19),10(21),11,13,16(20),17-hexaen-7-one
Technical Specifications
| Molecular Formula | C18H16O5 |
| Molecular Weight | 312.09976 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 68.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 312.09976 Da |
| Heavy Atoms | 23 |
| Complexity | 431.0 |
| SMILES | C1CC(=O)OCC2C(O2)C3=CC=C(C=C3)OC4=C(C=CC1=C4)O |
| InChIKey | COGWIGJGNQCZPK-UHFFFAOYSA-N |
Chemical Property Profile of Combretastatin D1
Property Insights of Combretastatin D1
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Combretastatin D1. The TPSA of 68.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Combretastatin D1. Following Lipinski's Rule of Five, Combretastatin D1 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Combretastatin D1?
The CAS number of Combretastatin D1 is 117709-78-1.
What is the molecular formula of Combretastatin D1?
The molecular formula of Combretastatin D1 is C18H16O5.
What is the molecular weight of Combretastatin D1?
The molecular weight of Combretastatin D1 is 312.09976 g/mol.
Where can I buy Combretastatin D1?
You can request a quote for Combretastatin D1 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Combretastatin D1?
Yes, CoreyChem provides custom synthesis services for Combretastatin D1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.