(2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide
TL;DR: (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide (CAS 117837-26-0) is a chemical compound with molecular formula C10H8N2OS2 and molecular weight 236.00781 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E)-N-(1,3-thiazol-2-yl)-3-thiophen-2-ylprop-2-enamide
Also Known As: (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide, (E)-N-(thiazol-2-yl)-3-(thiophen-2-yl)acrylamide, (E)-N-(1,3-thiazol-2-yl)-3-thiophen-2-ylprop-2-enamide, F1736-0621, N-(1,3-thiazol-2-yl)-(E)-3-(2-thienyl)acrylamide
Technical Specifications
| Molecular Formula | C10H8N2OS2 |
| Molecular Weight | 236.00781 g/mol |
| XLogP | 2.3 |
| Topological Polar Surface Area (TPSA) | 98.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 236.00781 Da |
| Heavy Atoms | 15 |
| Complexity | 258.0 |
| SMILES | C1=CSC(=C1)/C=C/C(=O)NC2=NC=CS2 |
| InChIKey | HXJMWXZUPOLKIM-ONEGZZNKSA-N |
Chemical Property Profile of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide
Property Insights of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide. The TPSA of 98.5 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide. Following Lipinski's Rule of Five, (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide is 117837-26-0.
What is the molecular formula of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide is C10H8N2OS2.
What is the molecular weight of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide is 236.00781 g/mol.
Where can I buy (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide?
Yes, CoreyChem provides custom synthesis services for (2E)-N-(1,3-thiazol-2-yl)-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.