4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide
TL;DR: 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide (CAS 117911-71-4) is a chemical compound with molecular formula C14H12F3NO2S and molecular weight 315.05408 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-methyl-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide
Also Known As: 4-Methyl-N-[4-(trifluoromethyl)phenyl]benzene-1-sulfonamide, 4-methyl-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide, 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide, N-(4-Trifluoromethylphenyl)-p-toluenesulfonamide, J1.858.947H
Technical Specifications
| Molecular Formula | C14H12F3NO2S |
| Molecular Weight | 315.05408 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 54.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 315.05408 Da |
| Heavy Atoms | 21 |
| Complexity | 428.0 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)C(F)(F)F |
| InChIKey | PPXMHTWGFXWJNR-UHFFFAOYSA-N |
Chemical Property Profile of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide
Property Insights of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide
The XLogP value of 3.7 indicates that 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.6 Ų, 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide?
The CAS number of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide is 117911-71-4.
What is the molecular formula of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide?
The molecular formula of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide is C14H12F3NO2S.
What is the molecular weight of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide?
The molecular weight of 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide is 315.05408 g/mol.
Where can I buy 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide?
You can request a quote for 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide?
Yes, CoreyChem provides custom synthesis services for 4-Methyl-N-(4-(trifluoromethyl)phenyl)benzenesulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.