1,3,3-Trimethyl-2-methyleneindoline
TL;DR: 1,3,3-Trimethyl-2-methyleneindoline (CAS 118-12-7) is a chemical compound with molecular formula C12H15N and molecular weight 173.12045 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,3,3-trimethyl-2-methylideneindole
Also Known As: 1,3,3-Trimethyl-2-methyleneindoline, Fischer's base, Fischer base, Fischers Base, Fischer's methylene base
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H15N |
| Molecular Weight | 173.12045 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 173.12045 Da |
| Heavy Atoms | 13 |
| Complexity | 229.0 |
| SMILES | CC1(C(=C)N(C2=CC=CC=C21)C)C |
| InChIKey | ZTUKGBOUHWYFGC-UHFFFAOYSA-N |
Product Description
Applications: 1,3,3-Trimethyl-2-methyleneindoline is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as dye and pigment synthesis and coloration chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1,3,3-Trimethyl-2-methyleneindoline (CAS 118-12-7) is a heterocyclic building block with the molecular formula C12H15N and a molecular weight of 173.12 g/mol. Synonyms include 1,3,3-Trimethyl-2-methyleneindoline and Fischer's base.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1,3,3-Trimethyl-2-methyleneindoline
Property Insights of 1,3,3-Trimethyl-2-methyleneindoline
The XLogP value of 3.4 indicates that 1,3,3-Trimethyl-2-methyleneindoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, 1,3,3-Trimethyl-2-methyleneindoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,3,3-Trimethyl-2-methyleneindoline has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1,3,3-Trimethyl-2-methyleneindoline?
The CAS number of 1,3,3-Trimethyl-2-methyleneindoline is 118-12-7.
What is the molecular formula of 1,3,3-Trimethyl-2-methyleneindoline?
The molecular formula of 1,3,3-Trimethyl-2-methyleneindoline is C12H15N.
What is the molecular weight of 1,3,3-Trimethyl-2-methyleneindoline?
The molecular weight of 1,3,3-Trimethyl-2-methyleneindoline is 173.12045 g/mol.
What are the applications of 1,3,3-Trimethyl-2-methyleneindoline?
1,3,3-Trimethyl-2-methyleneindoline is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as dye and pigment synthesis and coloration chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both...
Where can I buy 1,3,3-Trimethyl-2-methyleneindoline?
You can request a quote for 1,3,3-Trimethyl-2-methyleneindoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1,3,3-Trimethyl-2-methyleneindoline?
Yes, CoreyChem provides custom synthesis services for 1,3,3-Trimethyl-2-methyleneindoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.