5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
TL;DR: 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one (CAS 1181082-26-7) is a chemical compound with molecular formula C15H16N2O2S and molecular weight 288.09326 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5Z)-5-[(3-hydroxyphenyl)methylidene]-2-piperidin-1-yl-1,3-thiazol-4-one
Also Known As: BIM-0034129.P001, 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one, AB00097820-01, (5Z)-5-[(3-Hydroxyphenyl)methylene]-2-(1-piperidinyl)-4(5H)-thiazolone, (5Z)-5-(3-hydroxybenzylidene)-2-(piperidin-1-yl)-1,3-thiazol-4(5H)-one
Technical Specifications
| Molecular Formula | C15H16N2O2S |
| Molecular Weight | 288.09326 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 78.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 288.09326 Da |
| Heavy Atoms | 20 |
| Complexity | 441.0 |
| SMILES | C1CCN(CC1)C2=NC(=O)/C(=C/C3=CC(=CC=C3)O)/S2 |
| InChIKey | QEFSZHTXVNVMTG-RAXLEYEMSA-N |
Chemical Property Profile of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
Property Insights of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one. The TPSA of 78.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one. Following Lipinski's Rule of Five, 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The CAS number of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is 1181082-26-7.
What is the molecular formula of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The molecular formula of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is C15H16N2O2S.
What is the molecular weight of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
The molecular weight of 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one is 288.09326 g/mol.
Where can I buy 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
You can request a quote for 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one?
Yes, CoreyChem provides custom synthesis services for 5-(3-hydroxybenzylidene)-2-(1-piperidinyl)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.