KW 2149
TL;DR: KW 2149 (CAS 118359-59-4) is a chemical compound with molecular formula C24H34N6O8S2 and molecular weight 598.1879 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-amino-5-[2-[2-[[(4S,6S,7R,8S)-8-(carbamoyloxymethyl)-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-11-yl]amino]ethyldisulfanyl]ethylamino]-5-oxopentanoic acid
Also Known As: KW 2149, KT 6149, Mitomycin C derivatives (cancer), Kyowa, 7-N-(2-((2-(gamma-L-Glutamylamino)ethyl)dithio)ethyl)mitomycin C, 7-N-((2-((2-(R-L-Glutamylamino)ethyl)dithio)ethyl))mitomycin C
Technical Specifications
| Molecular Formula | C24H34N6O8S2 |
| Molecular Weight | 598.1879 g/mol |
| XLogP | -3.6 |
| Topological Polar Surface Area (TPSA) | 276.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 16 |
| Exact Mass | 598.1879 Da |
| Heavy Atoms | 40 |
| Complexity | 1160.0 |
| SMILES | CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)NCCSSCCNC(=O)CC[C@@H](C(=O)O)N |
| InChIKey | BIOSTZMAOGCGSC-CYUGEGSCSA-N |
Chemical Property Profile of KW 2149
Property Insights of KW 2149
The XLogP value of -3.6 indicates that KW 2149 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 276.0 Ų indicates high polarity, suggesting KW 2149 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, KW 2149 has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of KW 2149?
The CAS number of KW 2149 is 118359-59-4.
What is the molecular formula of KW 2149?
The molecular formula of KW 2149 is C24H34N6O8S2.
What is the molecular weight of KW 2149?
The molecular weight of KW 2149 is 598.1879 g/mol.
Where can I buy KW 2149?
You can request a quote for KW 2149 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for KW 2149?
Yes, CoreyChem provides custom synthesis services for KW 2149 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.