PQ401
TL;DR: PQ401 (CAS 1184297-34-4) is a chemical compound with molecular formula C18H16ClN3O2 and molecular weight 341.0931 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Also Known As: PQ401, PQ 401, null, IGF-1R Inhibitor II, 1-(5-Chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
Technical Specifications
| Molecular Formula | C18H16ClN3O2 |
| Molecular Weight | 341.0931 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 63.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 341.0931 Da |
| Heavy Atoms | 24 |
| Complexity | 436.0 |
| SMILES | CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC |
| InChIKey | YBLWOZUPHDKFOT-UHFFFAOYSA-N |
Chemical Property Profile of PQ401
Property Insights of PQ401
The XLogP value of 3.8 indicates that PQ401 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.3 Ų falls within the moderate polarity range, balancing permeability and solubility for PQ401. Following Lipinski's Rule of Five, PQ401 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of PQ401?
The CAS number of PQ401 is 1184297-34-4.
What is the molecular formula of PQ401?
The molecular formula of PQ401 is C18H16ClN3O2.
What is the molecular weight of PQ401?
The molecular weight of PQ401 is 341.0931 g/mol.
Where can I buy PQ401?
You can request a quote for PQ401 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for PQ401?
Yes, CoreyChem provides custom synthesis services for PQ401 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.