jnj 10181457 dihydrochloride
TL;DR: jnj 10181457 dihydrochloride (CAS 1188547-18-3) is a chemical compound with molecular formula C20H28N2O and molecular weight 312.22015 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[[3-(4-piperidin-1-ylbut-1-ynyl)phenyl]methyl]morpholine
Also Known As: jnj 10181457 dihydrochloride, 4-(3-(4-(Piperidinyl)but-1-ynyl)benzyl)morpholine, JNJ 10181457, JNJ-10181457 (hydrochloride), JNJ-10181457 dihydrochloride
Technical Specifications
| Molecular Formula | C20H28N2O |
| Molecular Weight | 312.22015 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 15.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 312.22015 Da |
| Heavy Atoms | 23 |
| Complexity | 398.0 |
| SMILES | C1CCN(CC1)CCC#CC2=CC=CC(=C2)CN3CCOCC3 |
| InChIKey | HDRIBIYPLKZUDQ-UHFFFAOYSA-N |
Chemical Property Profile of jnj 10181457 dihydrochloride
Property Insights of jnj 10181457 dihydrochloride
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for jnj 10181457 dihydrochloride. With a topological polar surface area (TPSA) of 15.7 Ų, jnj 10181457 dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, jnj 10181457 dihydrochloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of jnj 10181457 dihydrochloride?
The CAS number of jnj 10181457 dihydrochloride is 1188547-18-3.
What is the molecular formula of jnj 10181457 dihydrochloride?
The molecular formula of jnj 10181457 dihydrochloride is C20H28N2O.
What is the molecular weight of jnj 10181457 dihydrochloride?
The molecular weight of jnj 10181457 dihydrochloride is 312.22015 g/mol.
Where can I buy jnj 10181457 dihydrochloride?
You can request a quote for jnj 10181457 dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for jnj 10181457 dihydrochloride?
Yes, CoreyChem provides custom synthesis services for jnj 10181457 dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.