Licofelone
TL;DR: Licofelone (CAS 1189427-04-0) is a chemical compound with molecular formula C23H22ClNO2 and molecular weight 379.1339 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[2-(4-chlorophenyl)-6,6-dimethyl-1-phenyl-5,7-dihydropyrrolizin-3-yl]acetic acid
Also Known As: Licofelone, licofelona, Licofelone [INN], licofelonum, null
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C23H22ClNO2 |
| Molecular Weight | 379.1339 g/mol |
| XLogP | 5.2 |
| Topological Polar Surface Area (TPSA) | 42.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 379.1339 Da |
| Heavy Atoms | 27 |
| Complexity | 536.0 |
| SMILES | CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C |
| InChIKey | UAWXGRJVZSAUSZ-UHFFFAOYSA-N |
Product Description
Applications: Licofelone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Licofelone (CAS 1189427-04-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Licofelone is a pharmaceutical intermediate identified by CAS number 1189427-04-0 and the molecular formula C23H22ClNO2 and a molecular weight of 379.13 g/mol. It is also known as Licofelone and licofelona.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Licofelone
Property Insights of Licofelone
The XLogP value of 5.2 indicates that Licofelone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.2 Ų, Licofelone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Licofelone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Licofelone?
The CAS number of Licofelone is 1189427-04-0.
What is the molecular formula of Licofelone?
The molecular formula of Licofelone is C23H22ClNO2.
What is the molecular weight of Licofelone?
The molecular weight of Licofelone is 379.1339 g/mol.
What are the applications of Licofelone?
Licofelone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Licofelone (CAS 1189427-04-0) with custom...
Where can I buy Licofelone?
You can request a quote for Licofelone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Licofelone?
Yes, CoreyChem provides custom synthesis services for Licofelone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.