6-Aza-2-thiouridine
TL;DR: 6-Aza-2-thiouridine (CAS 1191421-14-3) is a chemical compound with molecular formula C8H11N3O5S and molecular weight 261.04193 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-sulfanylidene-1,2,4-triazin-5-one
Also Known As: 6-Aza-2-thiouridine, 2-Thio-6-azauridine, NCI60_000992, 5-Hydroxy-2-pentofuranosyl-1,2,4-triazine-3(2H)-thione, as-Triazine-3,4H)-dione, 2-.beta.-D-ribofuranosyl-3-thio-
Technical Specifications
| Molecular Formula | C8H11N3O5S |
| Molecular Weight | 261.04193 g/mol |
| XLogP | -1.5 |
| Topological Polar Surface Area (TPSA) | 147.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 261.04193 Da |
| Heavy Atoms | 17 |
| Complexity | 376.0 |
| SMILES | C1=NN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O |
| InChIKey | TVCBDTCUOVDLNZ-UHFFFAOYSA-N |
Chemical Property Profile of 6-Aza-2-thiouridine
Property Insights of 6-Aza-2-thiouridine
The XLogP value of -1.5 indicates that 6-Aza-2-thiouridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 147.0 Ų indicates high polarity, suggesting 6-Aza-2-thiouridine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 6-Aza-2-thiouridine has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-Aza-2-thiouridine?
The CAS number of 6-Aza-2-thiouridine is 1191421-14-3.
What is the molecular formula of 6-Aza-2-thiouridine?
The molecular formula of 6-Aza-2-thiouridine is C8H11N3O5S.
What is the molecular weight of 6-Aza-2-thiouridine?
The molecular weight of 6-Aza-2-thiouridine is 261.04193 g/mol.
Where can I buy 6-Aza-2-thiouridine?
You can request a quote for 6-Aza-2-thiouridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-Aza-2-thiouridine?
Yes, CoreyChem provides custom synthesis services for 6-Aza-2-thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.