Trimethoprim Hydrochloride
TL;DR: Trimethoprim Hydrochloride (CAS 119365-28-5) is a chemical compound with molecular formula C14H19ClN4O3 and molecular weight 326.11456 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine;hydrochloride
Also Known As: Trimethoprim HCl, Trimplex, Primsol, TRIMETHOPRIM HYDROCHLORIDE, Proloprim
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H19ClN4O3 |
| Molecular Weight | 326.11456 g/mol |
| XLogP | 1.6794 |
| Topological Polar Surface Area (TPSA) | 106.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 326.11456 Da |
| Heavy Atoms | 22 |
| Complexity | 307.0 |
| SMILES | COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N.Cl |
| InChIKey | YLCCEQZHUHUYPA-UHFFFAOYSA-N |
Chemical Property Profile of Trimethoprim Hydrochloride
Property Insights of Trimethoprim Hydrochloride
The XLogP value of 1.6794 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trimethoprim Hydrochloride. The TPSA of 106.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Trimethoprim Hydrochloride. Following Lipinski's Rule of Five, Trimethoprim Hydrochloride has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trimethoprim Hydrochloride?
The CAS number of Trimethoprim Hydrochloride is 119365-28-5.
What is the molecular formula of Trimethoprim Hydrochloride?
The molecular formula of Trimethoprim Hydrochloride is C14H19ClN4O3.
What is the molecular weight of Trimethoprim Hydrochloride?
The molecular weight of Trimethoprim Hydrochloride is 326.11456 g/mol.
Where can I buy Trimethoprim Hydrochloride?
You can request a quote for Trimethoprim Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trimethoprim Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Trimethoprim Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.