11-Formyl-20(RS)-camptothecin
TL;DR: 11-Formyl-20(RS)-camptothecin (CAS 119464-27-6) is a chemical compound with molecular formula C21H16N2O5 and molecular weight 376.10593 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-6-carbaldehyde
Also Known As: 11-Formyl-20(RS)-camptothecin, NCI60_004654, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8-carboxaldehyde,4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0{2,11}.0{4,9}.0{15,20}]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-6-carbaldehyde
Technical Specifications
| Molecular Formula | C21H16N2O5 |
| Molecular Weight | 376.10593 g/mol |
| XLogP | 0.4 |
| Topological Polar Surface Area (TPSA) | 96.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.10593 Da |
| Heavy Atoms | 28 |
| Complexity | 818.0 |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C(C=CC5=C4)C=O)O |
| InChIKey | AMDHQGZVCWWZCS-UHFFFAOYSA-N |
Chemical Property Profile of 11-Formyl-20(RS)-camptothecin
Property Insights of 11-Formyl-20(RS)-camptothecin
The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 11-Formyl-20(RS)-camptothecin. The TPSA of 96.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 11-Formyl-20(RS)-camptothecin. Following Lipinski's Rule of Five, 11-Formyl-20(RS)-camptothecin has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 11-Formyl-20(RS)-camptothecin?
The CAS number of 11-Formyl-20(RS)-camptothecin is 119464-27-6.
What is the molecular formula of 11-Formyl-20(RS)-camptothecin?
The molecular formula of 11-Formyl-20(RS)-camptothecin is C21H16N2O5.
What is the molecular weight of 11-Formyl-20(RS)-camptothecin?
The molecular weight of 11-Formyl-20(RS)-camptothecin is 376.10593 g/mol.
Where can I buy 11-Formyl-20(RS)-camptothecin?
You can request a quote for 11-Formyl-20(RS)-camptothecin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 11-Formyl-20(RS)-camptothecin?
Yes, CoreyChem provides custom synthesis services for 11-Formyl-20(RS)-camptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.