(+)-Niguldipine
TL;DR: (+)-Niguldipine (CAS 120054-86-6) is a chemical compound with molecular formula C36H39N3O6 and molecular weight 609.2839 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Dexniguldipine, (R)-niguldipine, Dexniguldipino, dexniguldipinum, (+)-NIGULDIPINE
Technical Specifications
| Molecular Formula | C36H39N3O6 |
| Molecular Weight | 609.2839 g/mol |
| XLogP | 6.8 |
| Topological Polar Surface Area (TPSA) | 114.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 11 |
| Exact Mass | 609.2839 Da |
| Heavy Atoms | 45 |
| Complexity | 1100.0 |
| SMILES | CC1=C([C@H](C(=C(N1)C)C(=O)OCCCN2CCC(CC2)(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC |
| InChIKey | SVJMLYUFVDMUHP-MGBGTMOVSA-N |
Chemical Property Profile of (+)-Niguldipine
Property Insights of (+)-Niguldipine
The XLogP value of 6.8 indicates that (+)-Niguldipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (+)-Niguldipine. Following Lipinski's Rule of Five, (+)-Niguldipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of (+)-Niguldipine?
The CAS number of (+)-Niguldipine is 120054-86-6.
What is the molecular formula of (+)-Niguldipine?
The molecular formula of (+)-Niguldipine is C36H39N3O6.
What is the molecular weight of (+)-Niguldipine?
The molecular weight of (+)-Niguldipine is 609.2839 g/mol.
Where can I buy (+)-Niguldipine?
You can request a quote for (+)-Niguldipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (+)-Niguldipine?
Yes, CoreyChem provides custom synthesis services for (+)-Niguldipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.