rac-cis Dorzolamide Hydrochloride
TL;DR: rac-cis Dorzolamide Hydrochloride (CAS 120279-37-0) is a chemical compound with molecular formula C10H17ClN2O4S3 and molecular weight 360.0039 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide;hydrochloride
Also Known As: dorzolamide, Trusopt, Cosopt, Dorzolamide HCl, Dorzolomide hydrochloride
Technical Specifications
| Molecular Formula | C10H17ClN2O4S3 |
| Molecular Weight | 360.0039 g/mol |
| XLogP | 1.0338 |
| Topological Polar Surface Area (TPSA) | 151.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 360.0039 Da |
| Heavy Atoms | 20 |
| Complexity | 534.0 |
| SMILES | CCNC1CC(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl |
| InChIKey | OSRUSFPMRGDLAG-UHFFFAOYSA-N |
Chemical Property Profile of rac-cis Dorzolamide Hydrochloride
Property Insights of rac-cis Dorzolamide Hydrochloride
The XLogP value of 1.0338 suggests moderate lipophilicity, balancing water solubility and membrane permeability for rac-cis Dorzolamide Hydrochloride. The TPSA of 151.0 Ų indicates high polarity, suggesting rac-cis Dorzolamide Hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, rac-cis Dorzolamide Hydrochloride has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of rac-cis Dorzolamide Hydrochloride?
The CAS number of rac-cis Dorzolamide Hydrochloride is 120279-37-0.
What is the molecular formula of rac-cis Dorzolamide Hydrochloride?
The molecular formula of rac-cis Dorzolamide Hydrochloride is C10H17ClN2O4S3.
What is the molecular weight of rac-cis Dorzolamide Hydrochloride?
The molecular weight of rac-cis Dorzolamide Hydrochloride is 360.0039 g/mol.
Where can I buy rac-cis Dorzolamide Hydrochloride?
You can request a quote for rac-cis Dorzolamide Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for rac-cis Dorzolamide Hydrochloride?
Yes, CoreyChem provides custom synthesis services for rac-cis Dorzolamide Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.