Anastrozole
TL;DR: Anastrozole (CAS 120511-73-1) is a chemical compound with molecular formula C17H19N5 and molecular weight 293.16403 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
Also Known As: anastrozole, Arimidex, anastrazole, Anastrozol, Anastrole
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H19N5 |
| Molecular Weight | 293.16403 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 78.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 293.16403 Da |
| Heavy Atoms | 22 |
| Complexity | 456.0 |
| Melting Point | 81-82 °C |
| Solubility | 0.53 |
| SMILES | CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N |
| InChIKey | YBBLVLTVTVSKRW-UHFFFAOYSA-N |
Chemical Property Profile of Anastrozole
Property Insights of Anastrozole
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Anastrozole. The TPSA of 78.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Anastrozole. Following Lipinski's Rule of Five, Anastrozole has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Anastrozole?
The CAS number of Anastrozole is 120511-73-1.
What is the molecular formula of Anastrozole?
The molecular formula of Anastrozole is C17H19N5.
What is the molecular weight of Anastrozole?
The molecular weight of Anastrozole is 293.16403 g/mol.
Where can I buy Anastrozole?
You can request a quote for Anastrozole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Anastrozole?
Yes, CoreyChem provides custom synthesis services for Anastrozole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.