Trimethyl phosphite
TL;DR: Trimethyl phosphite (CAS 121-45-9) is a chemical compound with molecular formula C3H9O3P and molecular weight 124.02893 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
trimethyl phosphite
Also Known As: TRIMETHYL PHOSPHITE, Trimethylphosphite, Trimethoxyphosphine, Methyl phosphite, Trimethylfosfit
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H9O3P |
| Molecular Weight | 124.02893 g/mol |
| XLogP | 0.1 |
| Topological Polar Surface Area (TPSA) | 27.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 124.02893 Da |
| Heavy Atoms | 7 |
| Complexity | 31.0 |
| Melting Point | -108 °F (USCG, 1999) |
| Boiling Point | 232 °F at 760 mmHg (USCG, 1999) |
| Density | 1.046 at 68 °F (USCG, 1999) - Denser than water; will sink |
| Flash Point | 82 °F (USCG, 1999) |
| Vapor Pressure | 24 mmHg at 77 °F (NIOSH, 2024) |
| Refractive Index | Index of refraction: 1.4095 at 20 °C/D |
| Solubility | Reacts with water (NIOSH, 2024) |
| SMILES | COP(OC)OC |
| InChIKey | CYTQBVOFDCPGCX-UHFFFAOYSA-N |
Product Description
Applications: Trimethyl phosphite is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Trimethyl phosphite is a heterocyclic building block identified by CAS number 121-45-9 and the molecular formula C3H9O3P and a molecular weight of 124.03 g/mol. Physically, the compound has a density of 1.046 at 68 °F (USCG, 1999) - Denser than water; will sink g/cm³, a solubility: Reacts with water (NIOSH, 2024). Synonyms include TRIMETHYL PHOSPHITE and Trimethylphosphite.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trimethyl phosphite
Property Insights of Trimethyl phosphite
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trimethyl phosphite. With a topological polar surface area (TPSA) of 27.7 Ų, Trimethyl phosphite exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trimethyl phosphite has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trimethyl phosphite?
The CAS number of Trimethyl phosphite is 121-45-9.
What is the molecular formula of Trimethyl phosphite?
The molecular formula of Trimethyl phosphite is C3H9O3P.
What is the molecular weight of Trimethyl phosphite?
The molecular weight of Trimethyl phosphite is 124.02893 g/mol.
What are the applications of Trimethyl phosphite?
Trimethyl phosphite is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both...
Where can I buy Trimethyl phosphite?
You can request a quote for Trimethyl phosphite directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trimethyl phosphite?
Yes, CoreyChem provides custom synthesis services for Trimethyl phosphite and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.