2-Amino-5-Nitrothiazole
TL;DR: 2-Amino-5-Nitrothiazole (CAS 121-66-4) is a chemical compound with molecular formula C3H3N3O2S and molecular weight 144.9946 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-nitro-1,3-thiazol-2-amine
Also Known As: 2-AMINO-5-NITROTHIAZOLE, Enheptin, 5-Nitrothiazol-2-amine, Entramin, Amnizol soluble
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H3N3O2S |
| Molecular Weight | 144.9946 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 113.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 144.9946 Da |
| Heavy Atoms | 9 |
| Complexity | 125.0 |
| Melting Point | 396 °F (decomposes) (NTP, 1992) |
| Vapor Pressure | 0.000743 [mmHg] |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | C1=C(SC(=N1)N)[N+](=O)[O-] |
| InChIKey | MIHADVKEHAFNPG-UHFFFAOYSA-N |
Product Description
Applications: 2-Amino-5-Nitrothiazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as dye and pigment synthesis and coloration chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, 2-Amino-5-Nitrothiazole (CAS 121-66-4) has the molecular formula C3H3N3O2S and a molecular weight of 144.99 g/mol. Reported properties include a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). Synonyms include 2-AMINO-5-NITROTHIAZOLE and Enheptin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Amino-5-Nitrothiazole
Property Insights of 2-Amino-5-Nitrothiazole
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Amino-5-Nitrothiazole. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Amino-5-Nitrothiazole. Following Lipinski's Rule of Five, 2-Amino-5-Nitrothiazole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Amino-5-Nitrothiazole?
The CAS number of 2-Amino-5-Nitrothiazole is 121-66-4.
What is the molecular formula of 2-Amino-5-Nitrothiazole?
The molecular formula of 2-Amino-5-Nitrothiazole is C3H3N3O2S.
What is the molecular weight of 2-Amino-5-Nitrothiazole?
The molecular weight of 2-Amino-5-Nitrothiazole is 144.9946 g/mol.
What are the applications of 2-Amino-5-Nitrothiazole?
2-Amino-5-Nitrothiazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as dye and pigment synthesis and coloration chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 2-Amino-5-Nitrothiazole?
You can request a quote for 2-Amino-5-Nitrothiazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Amino-5-Nitrothiazole?
Yes, CoreyChem provides custom synthesis services for 2-Amino-5-Nitrothiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.