TL;DR: Leucyl-prolyl-proline (CAS 121305-26-8) is a chemical compound with molecular formula C16H27N3O4 and molecular weight 325.20016 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-1-[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Also Known As: H-LEU-PRO-PRO-OH, LPP Tripeptide, Leu-Pro-Pro, leucyl-prolyl-proline, L-Proline, 1-(1-L-leucyl-L-prolyl)-
| Molecular Formula | C16H27N3O4 |
| Molecular Weight | 325.20016 g/mol |
| XLogP | -1.7 |
| Topological Polar Surface Area (TPSA) | 104.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 325.20016 Da |
| Heavy Atoms | 23 |
| Complexity | 480.0 |
| SMILES | CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)O)N |
| InChIKey | DPURXCQCHSQPAN-AVGNSLFASA-N |
The XLogP value of -1.7 indicates that Leucyl-prolyl-proline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Leucyl-prolyl-proline. Following Lipinski's Rule of Five, Leucyl-prolyl-proline has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Leucyl-prolyl-proline is 121305-26-8.
The molecular formula of Leucyl-prolyl-proline is C16H27N3O4.
The molecular weight of Leucyl-prolyl-proline is 325.20016 g/mol.
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