TL;DR: hIAPP(22-27) (CAS 121341-41-1) is a chemical compound with molecular formula C30H47N7O8 and molecular weight 633.34863 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
Also Known As: NFGAIL, H-NFGAIL-OH, Amylin(22-27)[human], hIAPP(22-27), H-Asn-Phe-Gly-Ala-Ile-Leu-OH
| Molecular Formula | C30H47N7O8 |
| Molecular Weight | 633.34863 g/mol |
| XLogP | -2.5 |
| Topological Polar Surface Area (TPSA) | 252.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 19 |
| Exact Mass | 633.34863 Da |
| Heavy Atoms | 45 |
| Complexity | 1050.0 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)N)N |
| InChIKey | INZKWABEOBCYEL-HRBVALIDSA-N |
The XLogP value of -2.5 indicates that hIAPP(22-27) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 252.0 Ų indicates high polarity, suggesting hIAPP(22-27) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, hIAPP(22-27) has 8 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
The CAS number of hIAPP(22-27) is 121341-41-1.
The molecular formula of hIAPP(22-27) is C30H47N7O8.
The molecular weight of hIAPP(22-27) is 633.34863 g/mol.
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