5-Dimethylamiloride
TL;DR: 5-Dimethylamiloride (CAS 1214-79-5) is a chemical compound with molecular formula C8H12ClN7O and molecular weight 257.0792 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide
Also Known As: 5-dimethylamiloride, dimethylamiloride, Dimethyl amiloride, dimethyl amylioride, Dma cpd
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H12ClN7O |
| Molecular Weight | 257.0792 g/mol |
| XLogP | 0.1 |
| Topological Polar Surface Area (TPSA) | 137.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 257.0792 Da |
| Heavy Atoms | 17 |
| Complexity | 317.0 |
| SMILES | CN(C)C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N |
| InChIKey | RXMUPNVSYKGKMY-UHFFFAOYSA-N |
Product Description
Applications: 5-Dimethylamiloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
5-Dimethylamiloride (CAS 1214-79-5) is a pharmaceutical intermediate with the molecular formula C8H12ClN7O and a molecular weight of 257.08 g/mol. Synonyms include 5-dimethylamiloride and dimethylamiloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Dimethylamiloride
Property Insights of 5-Dimethylamiloride
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Dimethylamiloride. The TPSA of 137.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Dimethylamiloride. Following Lipinski's Rule of Five, 5-Dimethylamiloride has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Dimethylamiloride?
The CAS number of 5-Dimethylamiloride is 1214-79-5.
What is the molecular formula of 5-Dimethylamiloride?
The molecular formula of 5-Dimethylamiloride is C8H12ClN7O.
What is the molecular weight of 5-Dimethylamiloride?
The molecular weight of 5-Dimethylamiloride is 257.0792 g/mol.
What are the applications of 5-Dimethylamiloride?
5-Dimethylamiloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 5-Dimethylamiloride?
You can request a quote for 5-Dimethylamiloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Dimethylamiloride?
Yes, CoreyChem provides custom synthesis services for 5-Dimethylamiloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.