Fmoc-L-2,4,5-Trifluorophenylalanine
TL;DR: Fmoc-L-2,4,5-Trifluorophenylalanine (CAS 1217837-13-2) is a chemical compound with molecular formula C24H18F3NO4 and molecular weight 441.1188 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2,4,5-trifluorophenyl)propanoic acid
Also Known As: Fmoc-L-2,4,5-Trifluorophenylalanine, Fmoc-L-2,4,5-Trifluorophe, Fmoc-2,4,5-Trifluoro-L-Phenylalanine, (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4,5-trifluorophenyl)propanoic acid, Fmoc-Phe(2,4,5-F3)-OH
Technical Specifications
| Molecular Formula | C24H18F3NO4 |
| Molecular Weight | 441.1188 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 75.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 441.1188 Da |
| Heavy Atoms | 32 |
| Complexity | 658.0 |
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CC(=C(C=C4F)F)F)C(=O)O |
| InChIKey | YAHKXQSXDLBLDX-QFIPXVFZSA-N |
Chemical Property Profile of Fmoc-L-2,4,5-Trifluorophenylalanine
Property Insights of Fmoc-L-2,4,5-Trifluorophenylalanine
The XLogP value of 4.9 indicates that Fmoc-L-2,4,5-Trifluorophenylalanine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Fmoc-L-2,4,5-Trifluorophenylalanine. Following Lipinski's Rule of Five, Fmoc-L-2,4,5-Trifluorophenylalanine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Fmoc-L-2,4,5-Trifluorophenylalanine?
The CAS number of Fmoc-L-2,4,5-Trifluorophenylalanine is 1217837-13-2.
What is the molecular formula of Fmoc-L-2,4,5-Trifluorophenylalanine?
The molecular formula of Fmoc-L-2,4,5-Trifluorophenylalanine is C24H18F3NO4.
What is the molecular weight of Fmoc-L-2,4,5-Trifluorophenylalanine?
The molecular weight of Fmoc-L-2,4,5-Trifluorophenylalanine is 441.1188 g/mol.
Where can I buy Fmoc-L-2,4,5-Trifluorophenylalanine?
You can request a quote for Fmoc-L-2,4,5-Trifluorophenylalanine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Fmoc-L-2,4,5-Trifluorophenylalanine?
Yes, CoreyChem provides custom synthesis services for Fmoc-L-2,4,5-Trifluorophenylalanine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.