1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one
TL;DR: 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one (CAS 122664-43-1) is a chemical compound with molecular formula C18H16N2O2 and molecular weight 292.1212 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(4-hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one
Also Known As: BAS 01054332, J1.086.071G, 1-(4-hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one, AE-848/09036025, 1-(4-Hydroxy-phenyl)-2,6-dimethyl-5-phenyl-1H-pyrimidin-4-one
Technical Specifications
| Molecular Formula | C18H16N2O2 |
| Molecular Weight | 292.1212 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 292.1212 Da |
| Heavy Atoms | 22 |
| Complexity | 495.0 |
| SMILES | CC1=C(C(=O)N=C(N1C2=CC=C(C=C2)O)C)C3=CC=CC=C3 |
| InChIKey | LHBHESWJRRHZGU-UHFFFAOYSA-N |
Chemical Property Profile of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one
Property Insights of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one. With a topological polar surface area (TPSA) of 52.9 Ų, 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one?
The CAS number of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one is 122664-43-1.
What is the molecular formula of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one?
The molecular formula of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one is C18H16N2O2.
What is the molecular weight of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one?
The molecular weight of 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one is 292.1212 g/mol.
Where can I buy 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one?
You can request a quote for 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one?
Yes, CoreyChem provides custom synthesis services for 1-(4-Hydroxyphenyl)-2,6-dimethyl-5-phenylpyrimidin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.