9-Methoxycamptothecin
TL;DR: 9-Methoxycamptothecin (CAS 1226875-26-8) is a chemical compound with molecular formula C21H18N2O5 and molecular weight 378.12158 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(19R)-19-ethyl-19-hydroxy-8-methoxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Also Known As: 9-Methoxycamptothecin, Compound AK-693/40962731, (R)-4-ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (R)-4-Ethyl-4-hydroxy-10-methoxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
Technical Specifications
| Molecular Formula | C21H18N2O5 |
| Molecular Weight | 378.12158 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 89.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.12158 Da |
| Heavy Atoms | 28 |
| Complexity | 790.0 |
| SMILES | CC[C@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5OC)N=C4C3=C2)O |
| InChIKey | XVMZDZFTCKLZTF-OAQYLSRUSA-N |
Chemical Property Profile of 9-Methoxycamptothecin
Property Insights of 9-Methoxycamptothecin
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 9-Methoxycamptothecin. The TPSA of 89.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 9-Methoxycamptothecin. Following Lipinski's Rule of Five, 9-Methoxycamptothecin has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 9-Methoxycamptothecin?
The CAS number of 9-Methoxycamptothecin is 1226875-26-8.
What is the molecular formula of 9-Methoxycamptothecin?
The molecular formula of 9-Methoxycamptothecin is C21H18N2O5.
What is the molecular weight of 9-Methoxycamptothecin?
The molecular weight of 9-Methoxycamptothecin is 378.12158 g/mol.
Where can I buy 9-Methoxycamptothecin?
You can request a quote for 9-Methoxycamptothecin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 9-Methoxycamptothecin?
Yes, CoreyChem provides custom synthesis services for 9-Methoxycamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.