![2-[4-(Trifluoromethyl)phenyl]piperidine structure](/static/products/1228/1228570-26-0.webp)
2-[4-(Trifluoromethyl)phenyl]piperidine
TL;DR: 2-[4-(Trifluoromethyl)phenyl]piperidine (CAS 1228570-26-0) is a chemical compound with molecular formula C12H14F3N and molecular weight 229.10783 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[4-(trifluoromethyl)phenyl]piperidine
Also Known As: 2-[4-(trifluoromethyl)phenyl]piperidine, 2-(4-trifluoromethylphenyl)-piperidine, 2-(4-(trifluoromethyl)phenyl)piperidine, (2R)-2-[4-(trifluoromethyl)phenyl]piperidine, (2S)-2-[4-(trifluoromethyl)phenyl]piperidine
Technical Specifications
| Molecular Formula | C12H14F3N |
| Molecular Weight | 229.10783 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 229.10783 Da |
| Heavy Atoms | 16 |
| Complexity | 219.0 |
| SMILES | C1CCNC(C1)C2=CC=C(C=C2)C(F)(F)F |
| InChIKey | BPIPNPGHOKSKPH-UHFFFAOYSA-N |
Chemical Property Profile of 2-[4-(Trifluoromethyl)phenyl]piperidine
Property Insights of 2-[4-(Trifluoromethyl)phenyl]piperidine
The XLogP value of 3.1 indicates that 2-[4-(Trifluoromethyl)phenyl]piperidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, 2-[4-(Trifluoromethyl)phenyl]piperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(Trifluoromethyl)phenyl]piperidine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-[4-(Trifluoromethyl)phenyl]piperidine?
The CAS number of 2-[4-(Trifluoromethyl)phenyl]piperidine is 1228570-26-0.
What is the molecular formula of 2-[4-(Trifluoromethyl)phenyl]piperidine?
The molecular formula of 2-[4-(Trifluoromethyl)phenyl]piperidine is C12H14F3N.
What is the molecular weight of 2-[4-(Trifluoromethyl)phenyl]piperidine?
The molecular weight of 2-[4-(Trifluoromethyl)phenyl]piperidine is 229.10783 g/mol.
Where can I buy 2-[4-(Trifluoromethyl)phenyl]piperidine?
You can request a quote for 2-[4-(Trifluoromethyl)phenyl]piperidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-[4-(Trifluoromethyl)phenyl]piperidine?
Yes, CoreyChem provides custom synthesis services for 2-[4-(Trifluoromethyl)phenyl]piperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.