4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
TL;DR: 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 122929-23-1) is a chemical compound with molecular formula C9H12FN3O3 and molecular weight 229.08627 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-1-[3-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Also Known As: Cytosine,3'-dideoxy-2'-fluoro-, Cytidine,2',3'-dideoxy-2'-fluoro- (9CI), 4-amino-1-(2,3-dideoxy-2-fluoropentofuranosyl)pyrimidin-2(1h)-one, 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one, 4-amino-1-[3-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Technical Specifications
| Molecular Formula | C9H12FN3O3 |
| Molecular Weight | 229.08627 g/mol |
| XLogP | -0.9 |
| Topological Polar Surface Area (TPSA) | 88.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.08627 Da |
| Heavy Atoms | 16 |
| Complexity | 358.0 |
| SMILES | C1C(OC(C1F)N2C=CC(=NC2=O)N)CO |
| InChIKey | LTDCCBLBAQXNKP-UHFFFAOYSA-N |
Chemical Property Profile of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Property Insights of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
The XLogP value of -0.9 indicates that 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 88.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Following Lipinski's Rule of Five, 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one?
The CAS number of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one is 122929-23-1.
What is the molecular formula of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one?
The molecular formula of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one is C9H12FN3O3.
What is the molecular weight of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one?
The molecular weight of 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one is 229.08627 g/mol.
Where can I buy 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one?
You can request a quote for 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 4-Amino-1-(3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.