Sulfated amphotericin B
TL;DR: Sulfated amphotericin B (CAS 123113-03-1) is a chemical compound with molecular formula C47H75NO21S and molecular weight 1021.4552 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1S,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;sulfuric acid
Also Known As: Sulfated amphotericin B, Amphotericin B, sulfo deriv., SAB, (3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,35S)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid; sulfuric acid, (3R,4E,6E,8E,10E,12E,14E,16E,18S,19R,20R,21S,35S)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,12,14,16-heptaene-38-carboxylic acid; sulfuric acid
Technical Specifications
| Molecular Formula | C47H75NO21S |
| Molecular Weight | 1021.4552 g/mol |
| XLogP | 0.0589 |
| Topological Polar Surface Area (TPSA) | 403.0 Ų |
| Hydrogen Bond Donors | 14 |
| Hydrogen Bond Acceptors | 22 |
| Rotatable Bonds | 3 |
| Exact Mass | 1021.4552 Da |
| Heavy Atoms | 70 |
| Complexity | 1750.0 |
| SMILES | C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](CC2C(C(C[C@](O2)(CC(C(CCC(CC(CC(CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O.OS(=O)(=O)O |
| InChIKey | OCXLFNSKPKYRST-YDNQHMLDSA-N |
Chemical Property Profile of Sulfated amphotericin B
Property Insights of Sulfated amphotericin B
The XLogP value of 0.0589 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Sulfated amphotericin B. The TPSA of 403.0 Ų indicates high polarity, suggesting Sulfated amphotericin B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sulfated amphotericin B has 14 hydrogen bond donor(s) and 22 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Sulfated amphotericin B?
The CAS number of Sulfated amphotericin B is 123113-03-1.
What is the molecular formula of Sulfated amphotericin B?
The molecular formula of Sulfated amphotericin B is C47H75NO21S.
What is the molecular weight of Sulfated amphotericin B?
The molecular weight of Sulfated amphotericin B is 1021.4552 g/mol.
Where can I buy Sulfated amphotericin B?
You can request a quote for Sulfated amphotericin B directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sulfated amphotericin B?
Yes, CoreyChem provides custom synthesis services for Sulfated amphotericin B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.