Clofarabine
TL;DR: Clofarabine (CAS 123318-82-1) is a chemical compound with molecular formula C10H11ClFN5O3 and molecular weight 303.05344 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
Also Known As: Clofarabine, Clolar, Evoltra, Clofarex, clofarabina
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H11ClFN5O3 |
| Molecular Weight | 303.05344 g/mol |
| XLogP | 0.9 |
| Topological Polar Surface Area (TPSA) | 119.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 303.05344 Da |
| Heavy Atoms | 20 |
| Complexity | 370.0 |
| Solubility | 4.89e+00 g/L |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N |
| InChIKey | WDDPHFBMKLOVOX-AYQXTPAHSA-N |
Chemical Property Profile of Clofarabine
Property Insights of Clofarabine
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clofarabine. The TPSA of 119.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Clofarabine. Following Lipinski's Rule of Five, Clofarabine has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clofarabine?
The CAS number of Clofarabine is 123318-82-1.
What is the molecular formula of Clofarabine?
The molecular formula of Clofarabine is C10H11ClFN5O3.
What is the molecular weight of Clofarabine?
The molecular weight of Clofarabine is 303.05344 g/mol.
Where can I buy Clofarabine?
You can request a quote for Clofarabine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clofarabine?
Yes, CoreyChem provides custom synthesis services for Clofarabine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.