(Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one
TL;DR: (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one (CAS 1234351-90-6) is a chemical compound with molecular formula C16H12O4 and molecular weight 268.07355 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2Z)-6-hydroxy-2-[(4-methoxyphenyl)methylidene]-1-benzofuran-3-one
Also Known As: cKIT-IN-3, (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one, NP418, (2Z)-6-Hydroxy-2-(4-methoxybenzylidene)-1-benzofuran-3(2H)-one, (2Z)-6-hydroxy-2-[(4-methoxyphenyl)methylidene]-2,3-dihydro-1-benzofuran-3-one
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H12O4 |
| Molecular Weight | 268.07355 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 55.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 268.07355 Da |
| Heavy Atoms | 20 |
| Complexity | 395.0 |
| SMILES | COC1=CC=C(C=C1)/C=C\2/C(=O)C3=C(O2)C=C(C=C3)O |
| InChIKey | CVEOFOQULTXCSE-NVNXTCNLSA-N |
Chemical Property Profile of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one
Property Insights of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one
The XLogP value of 3.2 indicates that (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.8 Ų, (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one?
The CAS number of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one is 1234351-90-6.
What is the molecular formula of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one?
The molecular formula of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one is C16H12O4.
What is the molecular weight of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one?
The molecular weight of (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one is 268.07355 g/mol.
Where can I buy (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one?
You can request a quote for (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one?
Yes, CoreyChem provides custom synthesis services for (Z)-6-hydroxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.