5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride
TL;DR: 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride (CAS 123844-08-6) is a chemical compound with molecular formula C16H19ClN8O4 and molecular weight 422.12177 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl-[(2-methoxy-5-nitrophenyl)methyl]amino]pyrazine-2-carboxamide
Also Known As: Nenmba, 5-(N-Ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride, 5-N,N-Ethyl-(2-methoxy-5-nitrobenzyl)amiloride, L-651,548, L 651548
Technical Specifications
| Molecular Formula | C16H19ClN8O4 |
| Molecular Weight | 422.12177 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 192.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 422.12177 Da |
| Heavy Atoms | 29 |
| Complexity | 614.0 |
| SMILES | CCN(CC1=C(C=CC(=C1)[N+](=O)[O-])OC)C2=NC(=C(N=C2Cl)C(=O)N=C(N)N)N |
| InChIKey | CLODVYXNEXFMOL-UHFFFAOYSA-N |
Chemical Property Profile of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride
Property Insights of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride. The TPSA of 192.0 Ų indicates high polarity, suggesting 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride?
The CAS number of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride is 123844-08-6.
What is the molecular formula of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride?
The molecular formula of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride is C16H19ClN8O4.
What is the molecular weight of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride?
The molecular weight of 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride is 422.12177 g/mol.
Where can I buy 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride?
You can request a quote for 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride?
Yes, CoreyChem provides custom synthesis services for 5-(N-ethyl-(2'-methoxy-5'-nitrobenzyl))amiloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.