1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine
TL;DR: 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine (CAS 124424-26-6) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.08734 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,3S,4R,5S)-4-azido-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 1-Adfat, 2'-ara-FAZT, F-AZT, 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine, 1-(3-Azido-2,3-dideoxy-2-fluoro-beta-D-arabinofuranosyl)thymine
Technical Specifications
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.08734 g/mol |
| XLogP | 0.1 |
| Topological Polar Surface Area (TPSA) | 93.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 285.08734 Da |
| Heavy Atoms | 20 |
| Complexity | 518.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)N=[N+]=[N-])F |
| InChIKey | AVYGFRQPURLSLQ-JVZYCSMKSA-N |
Chemical Property Profile of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine
Property Insights of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine. The TPSA of 93.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine. Following Lipinski's Rule of Five, 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine?
The CAS number of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine is 124424-26-6.
What is the molecular formula of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine?
The molecular formula of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine is C10H12FN5O4.
What is the molecular weight of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine?
The molecular weight of 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine is 285.08734 g/mol.
Where can I buy 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine?
You can request a quote for 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine?
Yes, CoreyChem provides custom synthesis services for 1-(3-Azido-2,3-dideoxy-2-fluoroarabinofuranosyl)thymine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.