B-1 368
TL;DR: B-1 368 (CAS 124444-78-6) is a chemical compound with molecular formula C17H17ClF3N3O and molecular weight 371.10123 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
pyridin-3-yl-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone;hydrochloride
Also Known As: B-1 368, Piperazine, 1-(3-pyridinylcarbonyl)-4-(4-(trifluoromethyl)phenyl)-, monohydrochloride, 1-(3-Pyridinylcarbonyl)-4-(4-(trifluoromethyl)phenyl)piperazine monohydrochloride, pyridin-3-yl-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone hydrochloride, (Pyridin-3-yl){4-[4-(trifluoromethyl)phenyl]piperazin-1-yl}methanone--hydrogen chloride (1/1)
Technical Specifications
| Molecular Formula | C17H17ClF3N3O |
| Molecular Weight | 371.10123 g/mol |
| XLogP | 3.4846 |
| Topological Polar Surface Area (TPSA) | 36.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 371.10123 Da |
| Heavy Atoms | 25 |
| Complexity | 427.0 |
| SMILES | C1CN(CCN1C2=CC=C(C=C2)C(F)(F)F)C(=O)C3=CN=CC=C3.Cl |
| InChIKey | GPPOLZLTZJYUBU-UHFFFAOYSA-N |
Chemical Property Profile of B-1 368
Property Insights of B-1 368
The XLogP value of 3.4846 indicates that B-1 368 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.4 Ų, B-1 368 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, B-1 368 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of B-1 368?
The CAS number of B-1 368 is 124444-78-6.
What is the molecular formula of B-1 368?
The molecular formula of B-1 368 is C17H17ClF3N3O.
What is the molecular weight of B-1 368?
The molecular weight of B-1 368 is 371.10123 g/mol.
Where can I buy B-1 368?
You can request a quote for B-1 368 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for B-1 368?
Yes, CoreyChem provides custom synthesis services for B-1 368 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.