Aglepristone
TL;DR: Aglepristone (CAS 124478-60-0) is a chemical compound with molecular formula C29H37NO2 and molecular weight 431.28244 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: Aglepristone, Aglepristone [INN], (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one, (8S,11R,13S,14S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-13-methyl-17-[(Z)-prop-1-enyl]-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one, Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1Z)-1-propenyl-, (11.beta.,17.beta.)-
Technical Specifications
| Molecular Formula | C29H37NO2 |
| Molecular Weight | 431.28244 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 40.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 431.28244 Da |
| Heavy Atoms | 32 |
| Complexity | 858.0 |
| SMILES | C/C=C\[C@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O |
| InChIKey | RTCKAOKDXNYXEH-LMOUXUHNSA-N |
Chemical Property Profile of Aglepristone
Property Insights of Aglepristone
The XLogP value of 4.0 indicates that Aglepristone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, Aglepristone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Aglepristone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Aglepristone?
The CAS number of Aglepristone is 124478-60-0.
What is the molecular formula of Aglepristone?
The molecular formula of Aglepristone is C29H37NO2.
What is the molecular weight of Aglepristone?
The molecular weight of Aglepristone is 431.28244 g/mol.
Where can I buy Aglepristone?
You can request a quote for Aglepristone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Aglepristone?
Yes, CoreyChem provides custom synthesis services for Aglepristone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.