Losartan carboxylic acid
TL;DR: Losartan carboxylic acid (CAS 124750-92-1) is a chemical compound with molecular formula C22H21ClN6O2 and molecular weight 436.14145 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid
Also Known As: Losartan carboxylic acid, Carboxylosartan, EXP 3174, Losartancarboxylicacid, E-3174
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H21ClN6O2 |
| Molecular Weight | 436.14145 g/mol |
| XLogP | 5.0 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 436.14145 Da |
| Heavy Atoms | 31 |
| Complexity | 590.0 |
| SMILES | CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)Cl |
| InChIKey | ZEUXAIYYDDCIRX-UHFFFAOYSA-N |
Chemical Property Profile of Losartan carboxylic acid
Property Insights of Losartan carboxylic acid
The XLogP value of 5.0 indicates that Losartan carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Losartan carboxylic acid. Following Lipinski's Rule of Five, Losartan carboxylic acid has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Losartan carboxylic acid?
The CAS number of Losartan carboxylic acid is 124750-92-1.
What is the molecular formula of Losartan carboxylic acid?
The molecular formula of Losartan carboxylic acid is C22H21ClN6O2.
What is the molecular weight of Losartan carboxylic acid?
The molecular weight of Losartan carboxylic acid is 436.14145 g/mol.
Where can I buy Losartan carboxylic acid?
You can request a quote for Losartan carboxylic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Losartan carboxylic acid?
Yes, CoreyChem provides custom synthesis services for Losartan carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.