1-Chloro-4-(thiophen-2-yl)phthalazine
TL;DR: 1-Chloro-4-(thiophen-2-yl)phthalazine (CAS 124959-34-8) is a chemical compound with molecular formula C12H7ClN2S and molecular weight 246.00185 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-chloro-4-thiophen-2-ylphthalazine
Also Known As: 1-chloro-4-(thiophen-2-yl)phthalazine, 1-chloro-4-thien-2-ylphthalazine, 1-chloro-4-thiophen-2-ylphthalazine, 1-chloro-4-(2-thienyl)phthalazine, 2-(4-chlorophthalazinyl)thiophene
Technical Specifications
| Molecular Formula | C12H7ClN2S |
| Molecular Weight | 246.00185 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 54.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 246.00185 Da |
| Heavy Atoms | 16 |
| Complexity | 251.0 |
| SMILES | C1=CC=C2C(=C1)C(=NN=C2Cl)C3=CC=CS3 |
| InChIKey | RFNMBLLFIISECZ-UHFFFAOYSA-N |
Chemical Property Profile of 1-Chloro-4-(thiophen-2-yl)phthalazine
Property Insights of 1-Chloro-4-(thiophen-2-yl)phthalazine
The XLogP value of 3.4 indicates that 1-Chloro-4-(thiophen-2-yl)phthalazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.0 Ų, 1-Chloro-4-(thiophen-2-yl)phthalazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Chloro-4-(thiophen-2-yl)phthalazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Chloro-4-(thiophen-2-yl)phthalazine?
The CAS number of 1-Chloro-4-(thiophen-2-yl)phthalazine is 124959-34-8.
What is the molecular formula of 1-Chloro-4-(thiophen-2-yl)phthalazine?
The molecular formula of 1-Chloro-4-(thiophen-2-yl)phthalazine is C12H7ClN2S.
What is the molecular weight of 1-Chloro-4-(thiophen-2-yl)phthalazine?
The molecular weight of 1-Chloro-4-(thiophen-2-yl)phthalazine is 246.00185 g/mol.
Where can I buy 1-Chloro-4-(thiophen-2-yl)phthalazine?
You can request a quote for 1-Chloro-4-(thiophen-2-yl)phthalazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Chloro-4-(thiophen-2-yl)phthalazine?
Yes, CoreyChem provides custom synthesis services for 1-Chloro-4-(thiophen-2-yl)phthalazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.