Granisetron (JAN/USAN/INN)
TL;DR: Granisetron (JAN/USAN/INN) (CAS 124998-65-8) is a chemical compound with molecular formula C18H24N4O and molecular weight 312.195 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
Also Known As: granisetron, Sancuso, Sustol, exo-Granisetron, Kevatril
Technical Specifications
| Molecular Formula | C18H24N4O |
| Molecular Weight | 312.195 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 50.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 312.195 Da |
| Heavy Atoms | 23 |
| Complexity | 442.0 |
| SMILES | CN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C |
| InChIKey | MFWNKCLOYSRHCJ-AGUYFDCRSA-N |
Chemical Property Profile of Granisetron (JAN/USAN/INN)
Property Insights of Granisetron (JAN/USAN/INN)
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Granisetron (JAN/USAN/INN). With a topological polar surface area (TPSA) of 50.2 Ų, Granisetron (JAN/USAN/INN) exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Granisetron (JAN/USAN/INN) has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Granisetron (JAN/USAN/INN)?
The CAS number of Granisetron (JAN/USAN/INN) is 124998-65-8.
What is the molecular formula of Granisetron (JAN/USAN/INN)?
The molecular formula of Granisetron (JAN/USAN/INN) is C18H24N4O.
What is the molecular weight of Granisetron (JAN/USAN/INN)?
The molecular weight of Granisetron (JAN/USAN/INN) is 312.195 g/mol.
Where can I buy Granisetron (JAN/USAN/INN)?
You can request a quote for Granisetron (JAN/USAN/INN) directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Granisetron (JAN/USAN/INN)?
Yes, CoreyChem provides custom synthesis services for Granisetron (JAN/USAN/INN) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.