ICI-204448 (free acid)
TL;DR: ICI-204448 (free acid) (CAS 125190-72-9) is a chemical compound with molecular formula C23H26Cl2N2O4 and molecular weight 464.12695 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methylamino]-2-pyrrolidin-1-ylethyl]phenoxy]acetic acid
Also Known As: Ici 204448, ICI 204,448 hydrochloride, Lopac0_000704, ICI-204448 (free acid), ICI-204,448
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C23H26Cl2N2O4 |
| Molecular Weight | 464.12695 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 70.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 9 |
| Exact Mass | 464.12695 Da |
| Heavy Atoms | 31 |
| Complexity | 602.0 |
| SMILES | CN(C(CN1CCCC1)C2=CC(=CC=C2)OCC(=O)O)C(=O)CC3=CC(=C(C=C3)Cl)Cl |
| InChIKey | JKYJSFISYHSNOE-UHFFFAOYSA-N |
Product Description
Applications: ICI-204448 (free acid) is used in complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A organic building block supplied by CoreyChem, ICI-204448 (free acid) (CAS 125190-72-9) has the molecular formula C23H26Cl2N2O4 and a molecular weight of 464.13 g/mol. Synonyms include Ici 204448 and ICI 204,448 hydrochloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of ICI-204448 (free acid)
Property Insights of ICI-204448 (free acid)
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for ICI-204448 (free acid). The TPSA of 70.1 Ų falls within the moderate polarity range, balancing permeability and solubility for ICI-204448 (free acid). Following Lipinski's Rule of Five, ICI-204448 (free acid) has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of ICI-204448 (free acid)?
The CAS number of ICI-204448 (free acid) is 125190-72-9.
What is the molecular formula of ICI-204448 (free acid)?
The molecular formula of ICI-204448 (free acid) is C23H26Cl2N2O4.
What is the molecular weight of ICI-204448 (free acid)?
The molecular weight of ICI-204448 (free acid) is 464.12695 g/mol.
What are the applications of ICI-204448 (free acid)?
ICI-204448 (free acid) is used in complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical...
Where can I buy ICI-204448 (free acid)?
You can request a quote for ICI-204448 (free acid) directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for ICI-204448 (free acid)?
Yes, CoreyChem provides custom synthesis services for ICI-204448 (free acid) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.