TL;DR: Meridia (CAS 125494-59-9) is a chemical compound with molecular formula C17H29Cl2NO and molecular weight 333.16263 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine;hydrate;hydrochloride
Also Known As: Meridia, Sibutramine hydrochloride, Reductil, Sibutramine hydrochloride monohydrate, sibutramine
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C17H29Cl2NO |
| Molecular Weight | 333.16263 g/mol |
| XLogP | 4.34 |
| Topological Polar Surface Area (TPSA) | 4.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 333.16263 Da |
| Heavy Atoms | 21 |
| Complexity | 275.0 |
| SMILES | CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C.O.Cl |
| InChIKey | KFNNPQDSPLWLCX-UHFFFAOYSA-N |
The XLogP value of 4.34 indicates that Meridia is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 4.2 Ų, Meridia exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Meridia has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Meridia is 125494-59-9.
The molecular formula of Meridia is C17H29Cl2NO.
The molecular weight of Meridia is 333.16263 g/mol.
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