6-Chloro-4-(trifluoromethyl)nicotinic acid
TL;DR: 6-Chloro-4-(trifluoromethyl)nicotinic acid (CAS 1256359-11-1) is a chemical compound with molecular formula C7H3ClF3NO2 and molecular weight 224.98044 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-chloro-4-(trifluoromethyl)pyridine-3-carboxylic acid
Also Known As: 6-Chloro-4-(trifluoromethyl)nicotinic acid, 6-chloro-4-(trifluoromethyl)pyridine-3-carboxylic Acid, 3-Pyridinecarboxylic acid, 6-chloro-4-(trifluoromethyl)-, 6-CHLORO-4- NICOTINICACID, 6-CHLORO-4-(TRIFLUOROMETHYL)NICOTINICACID
Technical Specifications
| Molecular Formula | C7H3ClF3NO2 |
| Molecular Weight | 224.98044 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 50.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 224.98044 Da |
| Heavy Atoms | 14 |
| Complexity | 233.0 |
| SMILES | C1=C(C(=CN=C1Cl)C(=O)O)C(F)(F)F |
| InChIKey | BULUOEXUXOKCIG-UHFFFAOYSA-N |
Chemical Property Profile of 6-Chloro-4-(trifluoromethyl)nicotinic acid
Property Insights of 6-Chloro-4-(trifluoromethyl)nicotinic acid
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Chloro-4-(trifluoromethyl)nicotinic acid. With a topological polar surface area (TPSA) of 50.2 Ų, 6-Chloro-4-(trifluoromethyl)nicotinic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-4-(trifluoromethyl)nicotinic acid has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-Chloro-4-(trifluoromethyl)nicotinic acid?
The CAS number of 6-Chloro-4-(trifluoromethyl)nicotinic acid is 1256359-11-1.
What is the molecular formula of 6-Chloro-4-(trifluoromethyl)nicotinic acid?
The molecular formula of 6-Chloro-4-(trifluoromethyl)nicotinic acid is C7H3ClF3NO2.
What is the molecular weight of 6-Chloro-4-(trifluoromethyl)nicotinic acid?
The molecular weight of 6-Chloro-4-(trifluoromethyl)nicotinic acid is 224.98044 g/mol.
Where can I buy 6-Chloro-4-(trifluoromethyl)nicotinic acid?
You can request a quote for 6-Chloro-4-(trifluoromethyl)nicotinic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-Chloro-4-(trifluoromethyl)nicotinic acid?
Yes, CoreyChem provides custom synthesis services for 6-Chloro-4-(trifluoromethyl)nicotinic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.