NPF-etoposide
TL;DR: NPF-etoposide (CAS 125830-36-6) is a chemical compound with molecular formula C27H24FNO7 and molecular weight 493.1537 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5S,5aS,8aR,9R)-5-(4-fluoroanilino)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Also Known As: Npf-etoposide, 1,3-dioxol-6(5H)- one der., 4'-O-Demethyl-4-(4''-fluoroanilino)-4-desoxypodophyllotoxin, (5R-(5alpha,5abeta,8aalpha,9beta))-9-((4-Fluorophenyl)amino)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, (5S,5aS,8aR,9R)-5-(4-fluoroanilino)-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Technical Specifications
| Molecular Formula | C27H24FNO7 |
| Molecular Weight | 493.1537 g/mol |
| XLogP | 4.1 |
| Topological Polar Surface Area (TPSA) | 95.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 5 |
| Exact Mass | 493.1537 Da |
| Heavy Atoms | 36 |
| Complexity | 780.0 |
| SMILES | COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)NC6=CC=C(C=C6)F |
| InChIKey | OWZJVOYADMZDSO-LVEBQJTPSA-N |
Chemical Property Profile of NPF-etoposide
Property Insights of NPF-etoposide
The XLogP value of 4.1 indicates that NPF-etoposide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.5 Ų falls within the moderate polarity range, balancing permeability and solubility for NPF-etoposide. Following Lipinski's Rule of Five, NPF-etoposide has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of NPF-etoposide?
The CAS number of NPF-etoposide is 125830-36-6.
What is the molecular formula of NPF-etoposide?
The molecular formula of NPF-etoposide is C27H24FNO7.
What is the molecular weight of NPF-etoposide?
The molecular weight of NPF-etoposide is 493.1537 g/mol.
Where can I buy NPF-etoposide?
You can request a quote for NPF-etoposide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for NPF-etoposide?
Yes, CoreyChem provides custom synthesis services for NPF-etoposide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.