Manidipine dihydrochloride
TL;DR: Manidipine dihydrochloride (CAS 126372-04-1) is a chemical compound with molecular formula C35H40Cl2N4O6 and molecular weight 682.2325 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-[2-(4-benzhydrylpiperazin-1-yl)ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;dihydrochloride
Also Known As: Manidipine dihydrochloride, manidipine hydrochloride, Calslot, Manidipine 2HCl, Manidipine HCl
Application Areas
Top 5 of 6 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C35H40Cl2N4O6 |
| Molecular Weight | 682.2325 g/mol |
| XLogP | 5.7966 |
| Topological Polar Surface Area (TPSA) | 117.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 11 |
| Exact Mass | 682.2325 Da |
| Heavy Atoms | 47 |
| Complexity | 1090.0 |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl |
| InChIKey | JINNGBXKBDUGQT-UHFFFAOYSA-N |
Chemical Property Profile of Manidipine dihydrochloride
Property Insights of Manidipine dihydrochloride
The XLogP value of 5.7966 indicates that Manidipine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 117.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Manidipine dihydrochloride. Following Lipinski's Rule of Five, Manidipine dihydrochloride has 3 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Manidipine dihydrochloride?
The CAS number of Manidipine dihydrochloride is 126372-04-1.
What is the molecular formula of Manidipine dihydrochloride?
The molecular formula of Manidipine dihydrochloride is C35H40Cl2N4O6.
What is the molecular weight of Manidipine dihydrochloride?
The molecular weight of Manidipine dihydrochloride is 682.2325 g/mol.
Where can I buy Manidipine dihydrochloride?
You can request a quote for Manidipine dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Manidipine dihydrochloride?
Yes, CoreyChem provides custom synthesis services for Manidipine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.