![N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide structure](/static/products/126/1266365-40-5.webp)
N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
TL;DR: N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide (CAS 1266365-40-5) is a chemical compound with molecular formula C18H18F3N3O and molecular weight 349.1402 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
Also Known As: N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
Technical Specifications
| Molecular Formula | C18H18F3N3O |
| Molecular Weight | 349.1402 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 35.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 349.1402 Da |
| Heavy Atoms | 25 |
| Complexity | 427.0 |
| SMILES | C1CN(CCN1CC(=O)NC2=C(C=CC=C2F)F)C3=CC=C(C=C3)F |
| InChIKey | PMHKZRZBXWPGBE-UHFFFAOYSA-N |
Chemical Property Profile of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
Property Insights of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide
The XLogP value of 3.1 indicates that N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.6 Ų, N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide?
The CAS number of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide is 1266365-40-5.
What is the molecular formula of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide?
The molecular formula of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide is C18H18F3N3O.
What is the molecular weight of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide?
The molecular weight of N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide is 349.1402 g/mol.
Where can I buy N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide?
You can request a quote for N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide?
Yes, CoreyChem provides custom synthesis services for N-(2,6-difluorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.