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N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
TL;DR: N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (CAS 127243-85-0) is a chemical compound with molecular formula C20H20BrN3O2S and molecular weight 445.04596 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[2-[3-(4-bromophenyl)prop-2-enylamino]ethyl]isoquinoline-5-sulfonamide
Also Known As: H-89, Dihydrochloride, H-89 DIHYDROCHLORIDE, h-89, Protein kinase inhibitor H-89, H 89
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H20BrN3O2S |
| Molecular Weight | 445.04596 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 79.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 445.04596 Da |
| Heavy Atoms | 27 |
| Complexity | 570.0 |
| SMILES | C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br |
| InChIKey | ZKZXNDJNWUTGDK-UHFFFAOYSA-N |
Product Description
Applications: N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (CAS 127243-85-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide (CAS 127243-85-0) is a pharmaceutical intermediate with the molecular formula C20H20BrN3O2S and a molecular weight of 445.05 g/mol. It is also known as Kinome_2783 and H-89, Dihydrochloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
Property Insights of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide
The XLogP value of 3.5 indicates that N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.5 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide. Following Lipinski's Rule of Five, N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
The CAS number of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is 127243-85-0.
What is the molecular formula of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
The molecular formula of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is C20H20BrN3O2S.
What is the molecular weight of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
The molecular weight of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is 445.04596 g/mol.
What are the applications of N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
You can request a quote for N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide?
Yes, CoreyChem provides custom synthesis services for N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.