Sivelestat
TL;DR: Sivelestat (CAS 127373-66-4) is a chemical compound with molecular formula C20H22N2O7S and molecular weight 434.11478 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid
Also Known As: Sivelestat, Adalimumab, Elaspol, siberestat, sivelestatum
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H22N2O7S |
| Molecular Weight | 434.11478 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 147.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 434.11478 Da |
| Heavy Atoms | 30 |
| Complexity | 731.0 |
| SMILES | CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O |
| InChIKey | BTGNGJJLZOIYID-UHFFFAOYSA-N |
Chemical Property Profile of Sivelestat
Property Insights of Sivelestat
The XLogP value of 3.0 indicates that Sivelestat is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 147.0 Ų indicates high polarity, suggesting Sivelestat may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sivelestat has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Sivelestat?
The CAS number of Sivelestat is 127373-66-4.
What is the molecular formula of Sivelestat?
The molecular formula of Sivelestat is C20H22N2O7S.
What is the molecular weight of Sivelestat?
The molecular weight of Sivelestat is 434.11478 g/mol.
Where can I buy Sivelestat?
You can request a quote for Sivelestat directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sivelestat?
Yes, CoreyChem provides custom synthesis services for Sivelestat and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.