Ro 41-1049
TL;DR: Ro 41-1049 (CAS 127500-84-9) is a chemical compound with molecular formula C12H12FN3OS and molecular weight 265.0685 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2-Aminoethyl)-5-(3-fluorophenyl)thiazole-4-carboxamide
N-(2-aminoethyl)-5-(3-fluorophenyl)-1,3-thiazole-4-carboxamide
Also Known As: N-(2-Aminoethyl)-5-(3-fluorophenyl)thiazole-4-carboxamide, Ro 41-1049, Ro 41-1049 hydrochloride, Lopac-R-107, Ro-41-1049
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H12FN3OS |
| Molecular Weight | 265.0685 g/mol |
| XLogP | 1.4 |
| Topological Polar Surface Area (TPSA) | 96.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 265.0685 Da |
| Heavy Atoms | 18 |
| Complexity | 292.0 |
| SMILES | C1=CC(=CC(=C1)F)C2=C(N=CS2)C(=O)NCCN |
| InChIKey | SCKBPXUWGMKLDM-UHFFFAOYSA-N |
Product Description
Applications: Ro 41-1049 is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Ro 41-1049 (CAS 127500-84-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Ro 41-1049 is a heterocyclic building block identified by CAS number 127500-84-9 and the molecular formula C12H12FN3OS and a molecular weight of 265.07 g/mol. It is also known as N-(2-Aminoethyl)-5-(3-fluorophenyl)thiazole-4-carboxamide and Ro 41-1049.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Ro 41-1049
Property Insights of Ro 41-1049
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Ro 41-1049. The TPSA of 96.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 41-1049. Following Lipinski's Rule of Five, Ro 41-1049 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ro 41-1049?
The CAS number of Ro 41-1049 is 127500-84-9.
What is the molecular formula of Ro 41-1049?
The molecular formula of Ro 41-1049 is C12H12FN3OS.
What is the molecular weight of Ro 41-1049?
The molecular weight of Ro 41-1049 is 265.0685 g/mol.
What are the applications of Ro 41-1049?
Ro 41-1049 is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Ro 41-1049 (CAS 127500-84-9) with custom...
Where can I buy Ro 41-1049?
You can request a quote for Ro 41-1049 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ro 41-1049?
Yes, CoreyChem provides custom synthesis services for Ro 41-1049 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.